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CD24 antibody [SN3]

Name: CD24 antibody [SN3]
SKU: GTX74945_G10
Availability: BackOrder

GTX74945

ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Product group Antibodies

TargetCD24

Overview

Supplier
GeneTex
Product Name
CD24 antibody [SN3]
Delivery Days Customer
9
Application Supplier Note
FACS: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
SN3
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID100133941
Target name
CD24
Target description
CD24 molecule
Target synonyms
CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24A; signal transducer CD24
Host
Mouse
Isotype
IgG1
Protein IDP25063
Protein Name
Signal transducer CD24
Scientific Description
This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder.
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Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injury. Angelotti ML et al., 2012 Aug, Stem Cells
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Ovarian carcinoma tumor-initiating cells have a mesenchymal phenotype. Ricci F et al., 2012 May 15, Cell Cycle
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CD24: a novel surface marker for PDX1-positive pancreatic progenitors derived from human embryonic stem cells. Jiang W et al., 2011 Apr, Stem Cells
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Notch activation differentially regulates renal progenitors proliferation and differentiation toward the podocyte lineage in glomerular disorders. Lasagni L et al., 2010 Sep, Stem Cells
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Renal progenitor cells contribute to hyperplastic lesions of podocytopathies and crescentic glomerulonephritis. Smeets B et al., 2009 Dec, J Am Soc Nephrol
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Regeneration of glomerular podocytes by human renal progenitors. Ronconi E et al., 2009 Feb, J Am Soc Nephrol
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Targeting CD24 for treatment of colorectal and pancreatic cancer by monoclonal antibodies or small interfering RNA. Sagiv E et al., 2008 Apr 15, Cancer Res
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Isolation and characterization of multipotent progenitor cells from the Bowmans capsule of adult human kidneys. Sagrinati C et al., 2006 Sep, J Am Soc Nephrol
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