Bio-Connect

CD24 antibody [SN3]

GTX74945
GeneTex
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Mouse, Primate
TargetCD24
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD24 antibody [SN3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    FACS: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SN3
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID100133941
  • Target name
    CD24
  • Target description
    CD24 molecule
  • Target synonyms
    CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24A; signal transducer CD24
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP25063
  • Protein Name
    Signal transducer CD24
  • Scientific Description
    This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
  • Reactivity
    Human, Mouse, Primate
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder.
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  • Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injury. Angelotti ML et al., 2012 Aug, Stem Cells
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  • Ovarian carcinoma tumor-initiating cells have a mesenchymal phenotype. Ricci F et al., 2012 May 15, Cell Cycle
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  • CD24: a novel surface marker for PDX1-positive pancreatic progenitors derived from human embryonic stem cells. Jiang W et al., 2011 Apr, Stem Cells
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  • Notch activation differentially regulates renal progenitors proliferation and differentiation toward the podocyte lineage in glomerular disorders. Lasagni L et al., 2010 Sep, Stem Cells
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  • Renal progenitor cells contribute to hyperplastic lesions of podocytopathies and crescentic glomerulonephritis. Smeets B et al., 2009 Dec, J Am Soc Nephrol
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  • Regeneration of glomerular podocytes by human renal progenitors. Ronconi E et al., 2009 Feb, J Am Soc Nephrol
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  • Targeting CD24 for treatment of colorectal and pancreatic cancer by monoclonal antibodies or small interfering RNA. Sagiv E et al., 2008 Apr 15, Cancer Res
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  • Isolation and characterization of multipotent progenitor cells from the Bowmans capsule of adult human kidneys. Sagrinati C et al., 2006 Sep, J Am Soc Nephrol
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