CD24 antibody [SN3]
GTX74945
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
TargetCD24
Overview
- SupplierGeneTex
- Product NameCD24 antibody [SN3]
- Delivery Days Customer9
- Application Supplier NoteFACS: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSN3
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID100133941
- Target nameCD24
- Target descriptionCD24 molecule
- Target synonymsCD24A, signal transducer CD24, CD24 antigen (small cell lung carcinoma cluster 4 antigen)
- HostMouse
- IsotypeIgG1
- Protein IDP25063
- Protein NameSignal transducer CD24
- Scientific DescriptionThis gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Wang X, Liu M, Zhang J, et al. CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder. Cell Metab. 2022,34(8):1088-1103.e6. doi: 10.1016/j.cmet.2022.07.005Read this paper
- Angelotti ML, Ronconi E, Ballerini L, et al. Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injury. Stem Cells. 2012,30(8):1714-25. doi: 10.1002/stem.1130Read this paper
- Ricci F, Bernasconi S, Perego P, et al. Ovarian carcinoma tumor-initiating cells have a mesenchymal phenotype. Cell Cycle. 2012,11(10):1966-76. doi: 10.4161/cc.20308Read this paper
- Jiang W, Sui X, Zhang D, et al. CD24: a novel surface marker for PDX1-positive pancreatic progenitors derived from human embryonic stem cells. Stem Cells. 2011,29(4):609-17. doi: 10.1002/stem.608Read this paper
- Lasagni L, Ballerini L, Angelotti ML, et al. Notch activation differentially regulates renal progenitors proliferation and differentiation toward the podocyte lineage in glomerular disorders. Stem Cells. 2010,28(9):1674-85. doi: 10.1002/stem.492Read this paper
- Smeets B, Angelotti ML, Rizzo P, et al. Renal progenitor cells contribute to hyperplastic lesions of podocytopathies and crescentic glomerulonephritis. J Am Soc Nephrol. 2009,20(12):2593-603. doi: 10.1681/ASN.2009020132Read this paper
- Ronconi E, Sagrinati C, Angelotti ML, et al. Regeneration of glomerular podocytes by human renal progenitors. J Am Soc Nephrol. 2009,20(2):322-32. doi: 10.1681/ASN.2008070709Read this paper
- Sagiv E, Starr A, Rozovski U, et al. Targeting CD24 for treatment of colorectal and pancreatic cancer by monoclonal antibodies or small interfering RNA. Cancer Res. 2008,68(8):2803-12. doi: 10.1158/0008-5472.CAN-07-6463Read this paper
- Sagrinati C, Netti GS, Mazzinghi B, et al. Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys. J Am Soc Nephrol. 2006,17(9):2443-56.Read this paper
Datasheet
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