CD24 , Cynomolgus (HEK293, His)
HY-P704452
Protein IDI7GKK1
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameCD24 , Cynomolgus (HEK293, His)
- Delivery Days Customer5
- CertificationResearch Use Only
- Protein IDI7GKK1
- Protein NameMacaca fascicularis brain cDNA clone: QtrA-10559, similar to human CD24 antigen (small cell lung carcinoma cluster 4antigen) (CD24), mRNA, RefSeq: NM_013230.1
- Scientific DescriptionCD24 protein plays a pivotal role in cell differentiation across various cell types, with signaling potentially initiated by lectin-like ligand binding to CD24 carbohydrates, transduced through second messengers released from the GPI-anchor. CD24 also modulates B-cell activation responses, promoting AG-dependent B-cell proliferation and preventing terminal differentiation into antibody-forming cells. In association with SIGLEC10, CD24 contributes to the selective suppression of the immune response to DAMPs such as HMGB1, HSP70, and HSP90, suggesting a role in immune regulation. Additionally, CD24 is implicated in controlling autoimmunity, exhibiting cell-type-specific interactions with LYN and FGR in diverse cellular processes and immune regulation. CD24 Protein, Cynomolgus (HEK293, His) is the recombinant others-derived CD24 protein, expressed by HEK293, with C-His labeled tag.
- UNSPSC41116100