![CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF405S conjugate, 0.1mg/mL [26628-22-8] CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF405S conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2018/10/BNUB2395.jpeg)
CD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC042395
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetIL2RA
Overview
- SupplierBiotium
- Product NameCD25/ IL2RA (Activated Lymphocyte Marker) (IL2RA/2395), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDIL2RA/2395
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID3559
- Target nameIL2RA
- Target descriptioninterleukin 2 receptor subunit alpha
- Target synonymsCD25; IDDM10; IL-2 receptor subunit alpha; IL2R; IL-2R subunit alpha; IMD41; interleukin 2 receptor, alpha; interleukin-2 receptor subunit alpha; p55; TAC antigen; TCGFR
- HostMouse
- IsotypeIgG2b
- Protein IDP01589
- Protein NameInterleukin-2 receptor subunit alpha
- Scientific DescriptionThis antibody recognizes a protein of 55 kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1 adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R f chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex.CD25 antibodies detect three epitope regions, A, B and C. This MAb This antibody recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203