
Staining of 48hr LPS activated mouse spleen cells using CD134L antibody (GTX27434) and PE rat IgG1 isotype control.
CD252 antibody [OX-89]
GTX27434
ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityMouse
TargetTNFSF4
Overview
- SupplierGeneTex
- Product NameCD252 antibody [OX-89]
- Delivery Days Customer9
- Application Supplier NoteFor FACS: Use at an assay dependent dilution. For IHC-Fr: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.
- ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDOX-89
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7292
- Target nameTNFSF4
- Target descriptionTNF superfamily member 4
- Target synonymsCD134 ligand; CD134L; CD252; glycoprotein Gp34; GP34; OX40 antigen ligand; OX-40L; OX4OL; tax-transcriptionally activated glycoprotein 1 (34kD); TNLG2B; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor ligand 2B; tumor necrosis factor ligand superfamily member 4; tumor necrosis factor superfamily member 4; TXGP1
- HostRat
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq]
- ReactivityMouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203