CD26 Antibody

Biorbyt

CD26 Antibody

10

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT IHC-P, WB

Research Use Only

Monoclonal

DPP4/7415

Unconjugated

DPP4

dipeptidyl peptidase 4

ADABP, ADCP2, CD26, DPPIV, TP103, dipeptidyl peptidase 4, ADCP-2, DPP IV, Gly-Pro naphthylamidase, Post-proline dipeptidyl aminopeptidase IV, T-cell activation antigen CD26, Xaa-Pro-dipeptidylaminopeptidase, adenosine deaminase complexing protein 2, dipeptidyl peptidase IV, dipeptidylpeptidase 4, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)

Mouse

IgG2

Dipeptidyl peptidase 4

Recognizes a glycoprotein of 110kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this mAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

Human

-20°C

12352203