CD268 / BAFFR / TNFRSF13C(BAFFR/1557), CF740 conjugate, 0.1mg/mL

Biotium

CD268 / BAFFR / TNFRSF13C(BAFFR/1557), CF740 conjugate, 0.1mg/mL

16

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

BAFFR/1557

0.1 mg/ml

Other Conjugate

TNFRSF13C

TNF receptor superfamily member 13C

BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin, tumor necrosis factor receptor superfamily member 13C, B cell-activating factor receptor, BAFF receptor, BLyS receptor 3

IgG1

Tumor necrosis factor receptor superfamily member 13C

Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) ; also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

2°C to 8°C,RT

41116100