CD27 CHO-K1 Stable Recombinant Cell Line
60624
Product group (Cell) Culture
Overview
- SupplierBPS Bioscience
- Product NameCD27 CHO-K1 Stable Recombinant Cell Line
- Delivery Days Customer7
- CertificationResearch Use Only
- Scientific DescriptionCHO-K1 cell line expressing full length human CD27 (TNFRSF7). Expression is confirmed by real time qPCR and Western blot. Screening for antibodies recognizing CD27 and screening antibodies for binding affinities. Since CHO-K1 cells do not express endogenous CD27, this cell line serves as an excellent model for studying changes in CD27-mediated signaling pathways, such as NF-B, MAPK and SAPK/JNK.
- Storage InstructionLiquid Nitrogen
- UNSPSC12352207
References
- Akiba H et.al. (1998) CD27, a member of the tumor necrosis factor receptor superfamily, activates NF- B and stress-activated protein kinase/ c-Jun N-terminal kinase via TRAF2, TRAF5, and NF- B inducing kinase. J. Biol. Chem. 273: 13353
- Yamamoto H et.al. (1998) NF- B activation in CD27 signaling: Involvement of TNF receptor-associated factor in its signaling and identification of functional region of CD27. J. Immunology 161: 4753-4759