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CD3 antibody [OKT3] (FITC)

GTX79906-06
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Primate
TargetCD3D
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD3 antibody [OKT3] (FITC)
  • Delivery Days Customer
    9
  • Application Supplier Note
    FACS: 1 microg (5 microl) for 105-108 cells in 100 microl sample per test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    OKT3
  • Concentration
    0.2 mg/ml
  • Conjugate
    FITC
  • Gene ID915
  • Target name
    CD3D
  • Target description
    CD3 delta subunit of T-cell receptor complex
  • Target synonyms
    CD3-DELTA, CD3DELTA, IMD19, T3D, T-cell surface glycoprotein CD3 delta chain, CD3 antigen, delta subunit, CD3 delta, CD3d antigen, delta polypeptide (TiT3 complex), CD3d molecule, delta (CD3-TCR complex), OKT3, delta chain, T-cell receptor T3 delta chain
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP04234
  • Protein Name
    T-cell surface glycoprotein CD3 delta chain
  • Reactivity
    Human, Primate
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Sánchez-Villanueva JA, Rodríguez-Jorge O, Ramírez-Pliego O, et al. Contribution of ROS and metabolic status to neonatal and adult CD8+ T cell activation. PLoS One. 2019,14(12):e0226388. doi: 10.1371/journal.pone.0226388
    Read this paper
  • Majri SS, Fritz JM, Villarino AV, et al. STAT5B: A Differential Regulator of the Life and Death of CD4(+) Effector Memory T Cells. J Immunol. 2018,200(1):110-118. doi: 10.4049/jimmunol.1701133
    Read this paper
  • Haga-Friedman A, Horovitz-Fried M, Cohen CJ. Incorporation of transmembrane hydrophobic mutations in the TCR enhance its surface expression and T cell functional avidity. J Immunol. 2012,188(11):5538-46. doi: 10.4049/jimmunol.1103020
    Read this paper
  • Bikker A, Moret FM, Kruize AA, et al. IL-7 drives Th1 and Th17 cytokine production in patients with primary SS despite an increase in CD4 T cells lacking the IL-7Rα. Rheumatology (Oxford). 2012,51(6):996-1005. doi: 10.1093/rheumatology/ker448
    Read this paper
  • Bagnara D, Kaufman MS, Calissano C, et al. A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease. Blood. 2011,117(20):5463-72. doi: 10.1182/blood-2010-12-324210
    Read this paper
  • Nguyen V, Cao L, Lin JT, et al. A new approach for quantitative phosphoproteomic dissection of signaling pathways applied to T cell receptor activation. Mol Cell Proteomics. 2009,8(11):2418-31. doi: 10.1074/mcp.M800307-MCP200
    Read this paper
  • Bibollet-Ruche F, McKinney BA, Duverger A, et al. The quality of chimpanzee T-cell activation and simian immunodeficiency virus/human immunodeficiency virus susceptibility achieved via antibody-mediated T-cell receptor/CD3 stimulation is a function of the anti-CD3 antibody isotype. J Virol. 2008,82(20):10271-8. doi: 10.1128/JVI.01319-08
    Read this paper
  • Roura-Mir C, Catálfamo M, Cheng TY, et al. CD1a and CD1c activate intrathyroidal T cells during Graves' disease and Hashimoto's thyroiditis. J Immunol. 2005,174(6):3773-80.
    Read this paper
  • Sato Y, Mukai K, Watanabe S, et al. The AMeX method. A simplified technique of tissue processing and paraffin embedding with improved preservation of antigens for immunostaining. Am J Pathol. 1986,125(3):431-5.
    Read this paper