FACS analysis of human peripheral blood lymphocytes using GTX00598-02 CD3 epsilon antibody [UCHT1] (Biotin). Solid line : Primary antibody Dashed line : Biotin mouse IgG1 isotype control Antibody amount : 0.25 microg
FACS analysis of human peripheral blood lymphocytes using GTX00598-02 CD3 epsilon antibody [UCHT1] (Biotin). Solid line : Primary antibody Dashed line : Biotin mouse IgG1 isotype control Antibody amount : 0.25 microg
CD3 epsilon antibody [UCHT1] (Biotin)
GTX00598-02
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Primate
TargetCD3E
Overview
- SupplierGeneTex
- Product NameCD3 epsilon antibody [UCHT1] (Biotin)
- Delivery Days Customer9
- Antibody SpecificityThis antibody reacts with the epsilon chain of the CD3 complex.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDUCHT1
- Concentration0.5 mg/ml
- ConjugateBiotin
- Gene ID916
- Target nameCD3E
- Target descriptionCD3e molecule
- Target synonymsCD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule, epsilon (CD3-TCR complex); CD3-epsilon; IMD18; T3E; T-cell antigen receptor complex, epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; TCRE
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Primate
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Establishment and Characterization of Human Germline Stem Cell Line with Unlimited Proliferation Potentials and no Tumor Formation. Hou J et al., 2015 Nov 20, Sci RepRead more
- Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction. Zhao E et al., 2016 Jan, Nat ImmunolRead more
- A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. Kap YS et al., 2009 Dec, J Histochem CytochemRead more
- The lack of epithelial interleukin-7 and BAFF/BLyS gene expression in prostate cancer as a possible mechanism of tumor escape from immunosurveillance. Di Carlo E et al., 2009 May 1, Clin Cancer ResRead more
- Increased T-bet+ cytotoxic effectors and type I interferon-mediated processes in chronic graft-versus-host disease of the oral mucosa. Imanguli MM et al., 2009 Apr 9, BloodRead more
- Anti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: role of Hck tyrosine kinase and implications for AIDS dementia. Kim MO et al., 2006 Jan, J VirolRead more
- Lupus IgG VH4.34 antibodies bind to a 220-kDa glycoform of CD45/B220 on the surface of human B lymphocytes. Cappione AJ et al., 2004 Apr 1, J ImmunolRead more
- Selective targeting and timing of matrix metalloproteinase inhibition in post-myocardial infarction remodeling. Yarbrough WM et al., 2003 Oct 7, CirculationRead more
- The transmembrane protein-tyrosine phosphatase CD45 is associated with decreased insulin receptor signaling. Kulas DT et al., 1996 Jan 12, J Biol ChemRead more