Bio-Connect
FACS analysis of Jurkat cells using GTX83004 CD3 zeta antibody [4B10]. Green : CD3 zeta Purple : negative control
FACS analysis of Jurkat cells using GTX83004 CD3 zeta antibody [4B10]. Green : CD3 zeta Purple : negative control
FACS analysis of Jurkat cells using GTX83004 CD3 zeta antibody [4B10]. Green : CD3 zeta Purple : negative control

CD3 zeta antibody [4B10]

GTX83004
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCD247
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    CD3 zeta antibody [4B10]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FACS: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    4B10
  • Conjugate
    Unconjugated
  • Gene ID919
  • Target name
    CD247
  • Target description
    CD247 molecule
  • Target synonyms
    CD247 antigen, zeta subunit; CD3H; CD3Q; CD3Z; CD3Z antigen, zeta polypeptide (TiT3 complex); CD3-ZETA; CD3zeta chain; IMD25; T3Z; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor T3 zeta chain; T-cell surface glycoprotein CD3 zeta chain; TCR zeta chain; TCRZ
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP20963
  • Protein Name
    T-cell surface glycoprotein CD3 zeta chain
  • Scientific Description
    The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Mechanism of action of a T cell-dependent bispecific antibody as a breakthrough immunotherapy against refractory colorectal cancer with an oncogenic mutation. Kamakura D et al., 2021 Jan, Cancer Immunol Immunother
    Read more