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CD38 antibody [90] (FITC)

Research Use Only
GTX75084
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetCd38
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD38 antibody [90] (FITC)
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    90
  • Concentration
    0.5 mg/ml
  • Conjugate
    FITC
  • Gene ID12494
  • Target name
    Cd38
  • Target description
    CD38 antigen
  • Target synonyms
    2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38-r; Cd38-rs1; cyclic ADP-ribose hydrolase 1; I-19; NIM-R5 antigen
  • Host
    Rat
  • Isotype
    IgG2a
  • Scientific Description
    This gene encodes a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Knockout mice deficient for this gene display altered humoral immune responses. In addition, knockout mice exhibit higher locomotor activity and defects in nurturing and social behaviors. [provided by RefSeq, Sep 2015]
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • CD38 Causes Autophagic Flux Inhibition and Cardiac Dysfunction Through a Transcriptional Inhibition Pathway Under Hypoxia/Ischemia Conditions. Zhang X et al., 2020, Front Cell Dev Biol
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