CD38 antibody [90] (FITC)
GTX75084
Overview
- SupplierGeneTex
- Product NameCD38 antibody [90] (FITC)
- Delivery Days Customer9
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID90
- Concentration0.5 mg/ml
- ConjugateFITC
- Gene ID12494
- Target nameCd38
- Target descriptionCD38 antigen
- Target synonyms2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38-r; Cd38-rs1; cyclic ADP-ribose hydrolase 1; I-19; NIM-R5 antigen
- HostRat
- IsotypeIgG2a
- Scientific DescriptionThis gene encodes a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Knockout mice deficient for this gene display altered humoral immune responses. In addition, knockout mice exhibit higher locomotor activity and defects in nurturing and social behaviors. [provided by RefSeq, Sep 2015]
- ReactivityMouse
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- CD38 Causes Autophagic Flux Inhibition and Cardiac Dysfunction Through a Transcriptional Inhibition Pathway Under Hypoxia/Ischemia Conditions. Zhang X et al., 2020, Front Cell Dev BiolRead more