FACS analysis of human peripheral blood monocytes using GTX01499-08 CD38 antibody [HB7] (PE). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.125 microg (5 microl)
FACS analysis of human peripheral blood monocytes using GTX01499-08 CD38 antibody [HB7] (PE). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.125 microg (5 microl)
CD38 antibody [HB7] (PE)
GTX01499-08
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
TargetCD38
Overview
- SupplierGeneTex
- Product NameCD38 antibody [HB7] (PE)
- Delivery Days Customer9
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHB7
- Concentration0.025 mg/ml
- ConjugateRPE
- Gene ID952
- Target nameCD38
- Target descriptionCD38 molecule
- Target synonyms2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; CD38 antigen (p45); cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; NAD(+) nucleosidase
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry. Llinas L et al., 2011 Jan 30, Immunol LettRead more
- The metamorphosis of a molecule: from soluble enzyme to the leukocyte receptor CD38. Ferrero E et al., 1999 Feb, J Leukoc BiolRead more
- Human CD38, a cell-surface protein with multiple functions. Mehta K et al., 1996 Oct, FASEB JRead more
- Discontinuous expression of a membrane antigen (HB-7) during B lymphocyte differentiation. Tedder TF et al., 1984 Sep, Tissue AntigensRead more
- Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation. Jackson DG et al., 1990 Apr 1, J ImmunolRead more