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FACS analysis of human peripheral blood monocytes using GTX01499-08 CD38 antibody [HB7] (PE). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.125 microg (5 microl)
FACS analysis of human peripheral blood monocytes using GTX01499-08 CD38 antibody [HB7] (PE). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.125 microg (5 microl)
FACS analysis of human peripheral blood monocytes using GTX01499-08 CD38 antibody [HB7] (PE). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.125 microg (5 microl)

CD38 antibody [HB7] (PE)

GTX01499-08
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
TargetCD38
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD38 antibody [HB7] (PE)
  • Delivery Days Customer
    9
  • Application Supplier Note
    FACS: 0.125 microg (5 microl) for 105-108 cells in 100 microl sample per test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HB7
  • Concentration
    0.025 mg/ml
  • Conjugate
    RPE
  • Gene ID952
  • Target name
    CD38
  • Target description
    CD38 molecule
  • Target synonyms
    ADPRC 1, ADPRC1, cADPR1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, CD38 antigen (p45), NAD(+) nucleosidase, cluster of differentiation 38, cyclic ADP-ribose hydrolase 1, ecto-nicotinamide adenine dinucleotide glycohydrolase
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP28907
  • Protein Name
    ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
  • Scientific Description
    The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Llinàs L, Lázaro A, de Salort J, et al. Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry. Immunol Lett. 2011,134(2):113-21. doi: 10.1016/j.imlet.2010.10.009
    Read this paper
  • Ferrero E, Malavasi F. The metamorphosis of a molecule: from soluble enzyme to the leukocyte receptor CD38. J Leukoc Biol. 1999,65(2):151-61.
    Read this paper
  • Mehta K, Shahid U, Malavasi F. Human CD38, a cell-surface protein with multiple functions. FASEB J. 1996,10(12):1408-17.
    Read this paper
  • Tedder TF, Clement LT, Cooper MD. Discontinuous expression of a membrane antigen (HB-7) during B lymphocyte differentiation. Tissue Antigens. 1984,24(3):140-9.
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  • Jackson DG, Bell JI. Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation. J Immunol. 1990,144(7):2811-5.
    Read this paper