CD4 antibody [EM4]

GeneTex

CD4 antibody [EM4]

9

Flow Cytometry, ImmunoPrecipitation, Western Blot

Research Use Only

Monoclonal

EM4

1 mg/ml

Unconjugated

CD4

CD4 molecule

CD4mut, IMD79, Leu-3, OKT4D, T4, T-cell surface glycoprotein CD4, CD4 antigen (p55), CD4 receptor, T-cell surface antigen T4/Leu-3

Mouse

IgG2a

T-cell surface glycoprotein CD4

This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]

Human

2°C to 8°C

12352203