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ProductsBack/CD40 antibody [FGK4.5/ FGK45]

CD40 antibody [FGK4.5/ FGK45]

GTX01483
GeneTex
ApplicationsFlow Cytometry
DownloadDatasheet
Product group Antibodies
TargetCd40
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD40 antibody [FGK4.5/ FGK45]
  • Delivery Days Customer
    9
  • Application Supplier Note
    *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    FGK4.5/ FGK45
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID21939
  • Target name
    Cd40
  • Target description
    CD40 antigen
  • Target synonyms
    AI326936; B-cell surface antigen CD40; Bp5; Bp50; CD40L receptor; GP39; HIGM1; IGM; IMD3; p5; p50; T-BAM; T-cell differentiation antigen; Tnfr; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5
  • Host
    Rat
  • Isotype
    IgG2a
  • Protein IDP27512
  • Protein Name
    Tumor necrosis factor receptor superfamily member 5
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Agonistic anti-CD40 antibody profoundly suppresses the immune response to infection with lymphocytic choriomeningitis virus. Bartholdy C et al., 2007 Feb 1, J Immunol
    Read more
  • IL-10- and IL-12-independent down-regulation of allergic sensitization by stimulation of CD40 signaling. Hellings PW et al., 2006 Oct 15, J Immunol
    Read more
  • Therapeutic activity of agonistic monoclonal antibodies against CD40 in a chronic autoimmune inflammatory process. Mauri C et al., 2000 Jun, Nat Med
    Read more
  • Disruption of CD154:CD40 blocks generation of allograft immunity without affecting APC activation. Shepherd DM et al., 1999 Sep 1, J Immunol
    Read more

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Figure 2. IHC analysis of CD40/TNFRSF5 using anti-CD40/TNFRSF5 antibody (PB10052). CD40/TNFRSF5 was detected in a paraffin-embedded section of mouse lymphaden tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1 microg/ml rabbit anti-CD40/TNFRSF5 Antibody (PB10052) overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) (Catalog # SA1022) with DAB as the chromogen.
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