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ProductsBack/CD40 Polyclonal Antibody

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CD40 Polyclonal Antibody at dilution 1:70

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CD40 Polyclonal Antibody at dilution 1:70

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CD40 Polyclonal Antibody at dilution 1:70

CD40 Polyclonal Antibody

E-AB-16318

Product group Antibodies

Overview

Supplier
Elabscience
Product Name
CD40 Polyclonal Antibody
Delivery Days Customer
12
Applications Supplier
ELISA IHC
Certification
Research Use Only
Concentration
1.3mg/ml
Scientific Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, whicHuman, Mouseay be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.
UNSPSC
12352203

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