CD40L/CD154/TRAP, Rabbit (His)

MedChem Express

CD40L/CD154/TRAP, Rabbit (His)

10

Research Use Only

94.00

CD40LG

CD40 ligand

TNLG8B, CD40 ligand, tumor necrosis factor ligand 8B

CD40 ligand

CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis[1]. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-kappaB/MAPK pathway[2][3]. CD40L also involves in B cell differentiation, maturation, and apoptosis[4]. CD40L in Rabbit, cleaved into a soluble form, acts as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Protein, Rabbit (His) has a total length of 149 amino acids (M113-L261), is expressed in E. coli cells with N-terminal 6*His-tag.

-20°C

41116100