CD41 antibody [N2C1], Internal
GTX113758
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetITGA2B
Overview
- SupplierGeneTex
- Product NameCD41 antibody [N2C1], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.25 mg/ml
- ConjugateUnconjugated
- Gene ID3674
- Target nameITGA2B
- Target descriptionintegrin subunit alpha 2b
- Target synonymsBDPLT16, BDPLT2, CD41, CD41B, FMAIT2, GP2B, GPIIb, GT, GT1, GTA, HPA3, PPP1R93, integrin alpha-IIb, GPalpha IIb, alphaIIb protein, integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), platelet fibrinogen receptor, alpha subunit, platelet glycoprotein IIb of IIb/IIIa complex, platelet membrane glycoprotein IIb, platelet-specific antigen BAK, protein phosphatase 1, regulatory subunit 93
- HostRabbit
- IsotypeIgG
- Protein IDP08514
- Protein NameIntegrin alpha-IIb
- Scientific DescriptionITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Luteolin inhibits GPVI-mediated platelet activation, oxidative stress, and thrombosis.Read more
- The formulation and characterization of 3D printed grafts as vascular access for potential use in hemodialysis. Cheng B et al., 2018 Apr 23, RSC AdvRead more
- Mitochondrial dysfunction associated with autophagy and mitophagy in cerebrospinal fluid cells of patients with delayed cerebral ischemia following subarachnoid hemorrhage. Youn DH et al., 2021 Aug 13, Sci RepRead more
- Platelet activation contributes to hypoxia-induced inflammation. Delaney C et al., 2021 Mar 1, Am J Physiol Lung Cell Mol PhysiolRead more
- Platelet activation in experimental murine neonatal pulmonary hypertension. Davizon-Castillo P et al., 2020 Mar, Physiol RepRead more
- Distribution of platelets, transforming growth factor-beta1, platelet-derived growth factor-BB, vascular endothelial growth factor and matrix metalloprotease-9 in advanced platelet-rich fibrin and concentrated growth factor matrices. Takahashi A et al., 2019 Nov, J Investig Clin DentRead more
- New evidence that a large proportion of human blood plasma cell-free DNA is localized in exosomes. Fernando MR et al., 2017, PLoS OneRead more
- Biomimicking Platelet-Monocyte Interactions as a Novel Targeting Strategy for Heart Healing. Cheng B et al., 2016 Oct, Adv Healthc MaterRead more
![FACS analysis of human peripheral blood using GTX15021 CD41a antibody [HIP8].](https://www.genetex.com/upload/website/prouct_img/normal/GTX15021/GTX15021_20191025_AP_006_126_w_23060620_673.webp)
![Surface staining of human platelets with anti-human CD41 [MEM-06] (PE).](https://www.genetex.com/upload/website/prouct_img/normal/GTX22211/Integrin-alpha-2b-antibody-MEM-06-GTX22211-FACS-1_w_23060620_358.webp)
![ELISA analysis of antigen using GTX60763 CD41 antibody [2E10C9]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng](https://www.genetex.com/upload/website/prouct_img/normal/GTX60763/GTX60763_20170912_ELISA_w_23061123_667.webp)
![ELISA analysis of antigen using GTX60764 CD41 antibody [2E10C9]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng](https://www.genetex.com/upload/website/prouct_img/normal/GTX60764/GTX60764_20170912_ELISA_w_23061123_274.webp)