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ProductsBack/CD41 antibody [N2C1], Internal

CD41 antibody [N2C1], Internal

GTX113758
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetITGA2B
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD41 antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.25 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3674
  • Target name
    ITGA2B
  • Target description
    integrin subunit alpha 2b
  • Target synonyms
    alphaIIb protein; BDPLT16; BDPLT2; CD41; CD41B; GP2B; GPalpha IIb; GPIIb; GT; GT1; GTA; HPA3; integrin alpha-IIb; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet-specific antigen BAK; PPP1R93; protein phosphatase 1, regulatory subunit 93
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP08514
  • Protein Name
    Integrin alpha-IIb
  • Scientific Description
    ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Luteolin inhibits GPVI-mediated platelet activation, oxidative stress, and thrombosis.
    Read more
  • The formulation and characterization of 3D printed grafts as vascular access for potential use in hemodialysis. Cheng B et al., 2018 Apr 23, RSC Adv
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  • Mitochondrial dysfunction associated with autophagy and mitophagy in cerebrospinal fluid cells of patients with delayed cerebral ischemia following subarachnoid hemorrhage. Youn DH et al., 2021 Aug 13, Sci Rep
    Read more
  • Platelet activation contributes to hypoxia-induced inflammation. Delaney C et al., 2021 Mar 1, Am J Physiol Lung Cell Mol Physiol
    Read more
  • Platelet activation in experimental murine neonatal pulmonary hypertension. Davizon-Castillo P et al., 2020 Mar, Physiol Rep
    Read more
  • Distribution of platelets, transforming growth factor-beta1, platelet-derived growth factor-BB, vascular endothelial growth factor and matrix metalloprotease-9 in advanced platelet-rich fibrin and concentrated growth factor matrices. Takahashi A et al., 2019 Nov, J Investig Clin Dent
    Read more
  • New evidence that a large proportion of human blood plasma cell-free DNA is localized in exosomes. Fernando MR et al., 2017, PLoS One
    Read more
  • Biomimicking Platelet-Monocyte Interactions as a Novel Targeting Strategy for Heart Healing. Cheng B et al., 2016 Oct, Adv Healthc Mater
    Read more