CD45RO antibody [UCHL1] (Biotin)

GeneTex

CD45RO antibody [UCHL1] (Biotin)

9

Recognizes the low molecular weight (Mr 180kDa) isoform of the leucocyte common antigen (LCA) which is part of a family of protein tryosine phosphatases. The CD45RO antigen is present on most thymocytes, about 40% of resting peripheral blood T-lymphocytes

When activated with phytohemagglutinin (PHA), naive T-cells lose the CD45RA antigen and begin to express the CD45RO antigen. Therefore, Anti-CD45RO may be a marker for memory T-cells. Anti-CD45RO may be used in formalin-fixed and paraffin-embedded tissues as well as frozen sections and cell suspensions. FACS: Use 1microg for 10^6 cells. Optimal dilutions/concentrations should be determined by the end user.

Flow Cytometry

Research Use Only

Monoclonal

UCHL1

0.1 mg/ml

Biotin

Liquid

PTPRC

protein tyrosine phosphatase receptor type C

B220; CD45; CD45 antigen; CD45R; GP180; LCA; L-CA; LY5; protein tyrosine phosphatase, receptor type, c polypeptide; receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen

Mouse

IgG2a

NK cells do not express the CD45RO antigen. It is also present on monocytes, macrophages and granulocytes.

Human

2°C to 8°C

12352203