CD4(C4/206), CF740 conjugate, 0.1mg/mL

Biotium

CD4(C4/206), CF740 conjugate, 0.1mg/mL

16

Flow Cytometry, ImmunoFluorescence

Research Use Only

Monoclonal

C4/206

0.1 mg/ml

Other Conjugate

CD4

CD4 molecule

CD4mut, IMD79, Leu-3, OKT4D, T4, T-cell surface glycoprotein CD4, CD4 antigen (p55), CD4 receptor, T-cell surface antigen T4/Leu-3

IgG1

T-cell surface glycoprotein CD4

Recognizes a protein of 55 kDa, identified as CD4. CD4 is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

2°C to 8°C,RT

41116100