CD54 / ICAM-1(F4-31C2), CF740 conjugate, 0.1mg/mL

Biotium

CD54 / ICAM-1(F4-31C2), CF740 conjugate, 0.1mg/mL

16

Research Use Only

Monoclonal

F4-31C2

0.1 mg/ml

Other Conjugate

ICAM1

intercellular adhesion molecule 1

BB2, CD54, P3.58, intercellular adhesion molecule 1, ICAM-1, cell surface glycoprotein P3.58, epididymis secretory sperm binding protein, intercellular adhesion molecule 1 (CD54), human rhinovirus receptor, major group rhinovirus receptor

IgG2a

Intercellular adhesion molecule 1

Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.

Animal

2°C to 8°C,RT

41116100