CD66e antibody

GeneTex

CD66e antibody

9

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

CEACAM5

CEA cell adhesion molecule 5

carcinoembryonic antigen related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CEA; meconium antigen 100

Chicken

IgY

Carcinoembryonic antigen-related cell adhesion molecule 5

The CEA gene family belongs to the immunoglobulin gene superfamily (IgSF) and comprises a large number of genes. The cell surface associated CEA proteins are heavily glycosylated, abundantly expressed and multifunctional. The human carcinoembryonic antigen (CEA) family can be divided into two subgroups according to the means of anchorage of member glycoproteins to the cell membrane: glycophosphatidyl inositol (GPI) linkage and transmembrane linkage. GPI-linked CEA family members include CEA (CD66e), non-specific cross-reacting antigen (NCA, CD66c), CEA gene-family members 6 (CGM6, CD66b) and 2 (CGM2). Transmembrane-linked members include biliary glycoprotein (BGP, Human C-CAM-L and C-CAM-S, CD66a), CGM1(CD66d) and CGM7. Recent evidence suggests the GPI-linked members tend to be up-regulated in human tumors, whereas the transmembrane-linked members tend to be down-regulated.

-20°C or -80°C,2°C to 8°C

12352203