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IHC-P analysis of human tonsil tissue using GTX20844 CD68 antibody [PG-M1] (ready-to-use).
IHC-P analysis of human tonsil tissue using GTX20844 CD68 antibody [PG-M1] (ready-to-use).
IHC-P analysis of human tonsil tissue using GTX20844 CD68 antibody [PG-M1] (ready-to-use).

CD68 antibody [PG-M1] (ready-to-use)

GTX20844
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCD68
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD68 antibody [PG-M1] (ready-to-use)
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    PG-M1
  • Conjugate
    Unconjugated
  • Gene ID968
  • Target name
    CD68
  • Target description
    CD68 molecule
  • Target synonyms
    CD68 antigen; GP110; LAMP4; macrophage antigen CD68; macrosialin; SCARD1; scavenger receptor class D, member 1
  • Host
    Mouse
  • Isotype
    IgG3
  • Protein IDP34810
  • Protein Name
    Macrosialin
  • Scientific Description
    This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • A Unique Cellular and Molecular Microenvironment Is Present in Tertiary Lymphoid Organs of Patients with Spontaneous Prostate Cancer Regression. Garcia-Hernandez ML et al., 2017, Front Immunol
    Read more
  • Suppressive Effects of Insulin on Tumor Necrosis Factor-Dependent Early Osteoarthritic Changes Associated With Obesity and Type 2 Diabetes Mellitus. Hamada D et al., 2016 Jun, Arthritis Rheumatol
    Read more