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ProductsBack/CD79B, Rat (HEK293, Fc)

CD79B, Rat (HEK293, Fc)

HY-P75658
MedChem Express
Protein IDO70153
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CD79B, Rat (HEK293, Fc)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Protein IDO70153
  • Protein Name
    B29/Ig-beta/CD79b
  • Scientific Description
    CD79B Protein, also known as B29 or Igbeta, is an essential component of the B cell receptor along with immunoglobulin and mb1 (Igalpha, CD79a) and is absolutely required for B cell development. Rat CD79B protein comprises 228 amino acids, and its amino acid sequence is 85 and 69% identical with the mouse and human counterparts, respectively. The B-cell antigen receptor (BCR) signaling component Igbeta (CD79B) and the co-receptor CD19 act as an alternative B-cell signaling module that promotes the survival of B lymphoma and normal B cells via integrated ITAM/PI3K signaling. The loss of CD79B causes a block in N-glycan maturation and accumulation of immature proteins[1][2][3]. CD79B Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD79B protein, expressed by HEK293 , with C-hFc labeled tag.
  • UNSPSC
    12352202