Bio-Connect

CD80 antibody [MEM-233]

GTX75761
GeneTex
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman, Monkey
TargetCD80
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD80 antibody [MEM-233]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody binds to residues within the Ig-v-like domain of human CD80 as shown by domain switching studies (Vasu et al. 2003).
  • Applications
    Flow Cytometry, ImmunoPrecipitation, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    MEM-233
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID941
  • Target name
    CD80
  • Target description
    CD80 molecule
  • Target synonyms
    activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP33681
  • Protein Name
    T-lymphocyte activation antigen CD80
  • Scientific Description
    The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]
  • Reactivity
    Human, Monkey
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis. Manferdini C et al., 2020 Dec 10, Biology (Basel)
    Read more
  • Effect of microfragmented adipose tissue on osteoarthritic synovial macrophage factors. Paolella F et al., 2019 Apr, J Cell Physiol
    Read more
  • From osteoarthritic synovium to synovial-derived cells characterization: synovial macrophages are key effector cells. Manferdini C et al., 2016 Apr 4, Arthritis Res Ther
    Read more
  • Rapamycin conditioning of dendritic cells differentiated from human ES cells promotes a tolerogenic phenotype. Silk KM et al., 2012, J Biomed Biotechnol
    Read more
  • The bacterial preparation OK432 induces IL-12p70 secretion in human dendritic cells in a TLR3 dependent manner. Hovden AO et al., 2012, PLoS One
    Read more
  • Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells. Silk KM et al., 2012 Oct, Gene Ther
    Read more
  • Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses. Hovden AO et al., 2011 Jan 5, BMC Immunol
    Read more
  • Immunological effects of sublingual immunotherapy: clinical efficacy is associated with modulation of programmed cell death ligand 1, IL-10, and IgG4. Piconi S et al., 2010 Dec 15, J Immunol
    Read more
  • Antisense anti IGF-I cellular therapy of malignant tumours: immune response in cancer patients. Trojan J et al., 2010 Oct, Biomed Pharmacother
    Read more
  • Differential effects of Paclitaxel on dendritic cell function. John J et al., 2010 Mar 19, BMC Immunol
    Read more