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FACS analysis of human peripheral blood lymphocytes using GTX43505 CD81 antibody [1D6].
FACS analysis of human peripheral blood lymphocytes using GTX43505 CD81 antibody [1D6].
FACS analysis of human peripheral blood lymphocytes using GTX43505 CD81 antibody [1D6].

CD81 antibody [1D6]

Research Use Only
GTX43505
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityGoat, Human, Primate, Sheep
TargetCD81
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD81 antibody [1D6]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:100-1:1000. ICC/IF: 1:100. IHC-P: 1:100. FACS: 1/5-1/10. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1D6
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID975
  • Target name
    CD81
  • Target description
    CD81 molecule
  • Target synonyms
    26 kDa cell surface protein TAPA-1; CD81 antigen; CD81 antigen (target of antiproliferative antibody 1); CVID6; S5.7; TAPA1; tetraspanin-28; TSPAN28; tspan-28
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP60033
  • Protein Name
    CD81 antigen
  • Scientific Description
    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  • Reactivity
    Goat, Human, Primate, Sheep
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Size and Concentration of Extracellular Vesicles in Pancreatic Juice From Patients With Pancreatic Ductal Adenocarcinoma. Nesteruk K et al., 2022 Feb 18, Clin Transl Gastroenterol
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  • Colorectal Cancer Cell-Derived Small Extracellular Vesicles Educate Human Fibroblasts to Stimulate Migratory Capacity. Clerici SP et al., 2021, Front Cell Dev Biol
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  • Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Rescue the Loss of Outer Hair Cells and Repair Cochlear Damage in Cisplatin-Injected Mice. Tsai SC et al., 2021 Jun 22, Int J Mol Sci
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  • Extracellular Vesicles from Caveolin-Enriched Microdomains Regulate Hyaluronan-Mediated Sustained Vascular Integrity. Mirzapoiazova T et al., 2015, Int J Cell Biol
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  • Epidermal growth factor receptor localized to exosome membranes as a possible biomarker for lung cancer diagnosis. Yamashita T et al., 2013 Dec, Pharmazie
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