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CD81 antibody

GTX101766
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
Product group Antibodies
TargetCD81
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD81 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID975
  • Target name
    CD81
  • Target description
    CD81 molecule
  • Target synonyms
    CVID6, S5.7, TAPA1, TSPAN28, CD81 antigen, 26 kDa cell surface protein TAPA-1, CD81 antigen (target of antiproliferative antibody 1), tetraspanin-28, tspan-28
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP60033
  • Protein Name
    CD81 antigen
  • Scientific Description
    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Duan TQ, Gao ZL, Luo AX, et al. Adipose mesenchymal stem cell-derived extracellular vesicles reduce glutamate-induced excitotoxicity in the retina. Neural Regen Res. 2023,18(10):2315-2320. doi: 10.4103/1673-5374.369123
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  • Tong L, Zhang S, Liu Q, et al. Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis. Sci Adv. 2023,9(15):eade5041. doi: 10.1126/sciadv.ade5041
    Read this paper
  • Liu Q, Hao H, Li J, et al. Oral Administration of Bovine Milk-Derived Extracellular Vesicles Attenuates Cartilage Degeneration via Modulating Gut Microbiota in DMM-Induced Mice. Nutrients. 2023,15(3). doi: 10.3390/nu15030747
    Read this paper
  • Ramos EK, Tsai CF, Jia Y, et al. Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity. Elife. 2022,11. doi: 10.7554/eLife.82669
    Read this paper
  • Hsu CH, Liu IF, Kuo HF, et al. miR-29a-3p/THBS2 Axis Regulates PAH-Induced Cardiac Fibrosis. Int J Mol Sci. 2021,22(19). doi: 10.3390/ijms221910574
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  • Tong L, Hao H, Zhang Z, et al. Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota. Theranostics. 2021,11(17):8570-8586. doi: 10.7150/thno.62046
    Read this paper
  • Liu X, Liu S, Luo D, et al. Involvement of Circulating Exosomal MicroRNAs in Jian-Pi-Yi-Shen Formula Protection Against Adenine-Induced Chronic Kidney Disease. Front Pharmacol. 2020,11:622658. doi: 10.3389/fphar.2020.622658
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  • Imai A, Oka S, Susuga M, et al. Comprehensive analysis and comparison of proteins in salivary exosomes of climacteric and adolescent females. Odontology. 2021,109(1):82-102. doi: 10.1007/s10266-020-00538-4
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  • Xue Y, Bhushan B, Mars WM, et al. Phosphorylated Ezrin (Thr567) Regulates Hippo Pathway and Yes-Associated Protein (Yap) in Liver. Am J Pathol. 2020,190(7):1427-1437. doi: 10.1016/j.ajpath.2020.03.014
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  • Tong L, Hao H, Zhang X, et al. Oral Administration of Bovine Milk-Derived Extracellular Vesicles Alters the Gut Microbiota and Enhances Intestinal Immunity in Mice. Mol Nutr Food Res. 2020,64(8):e1901251. doi: 10.1002/mnfr.201901251
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