CD8a Lentivirus

BPS Bioscience

CD8a Lentivirus

7

Research Use Only

CD8A

CD8 subunit alpha

CD8, CD8alpha, IMD116, Leu2, p32, T-cell surface glycoprotein CD8 alpha chain, CD8 antigen, alpha polypeptide (p32), CD8a molecule, Leu2 T-lymphocyte antigen, OKT8 T-cell antigen, T cell co-receptor, T-cell antigen Leu2, T-lymphocyte differentiation antigen T8/Leu-2, T8 T-cell antigen

un3373

T-cell surface glycoprotein CD8 alpha chain

CD8 (cluster of differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that functions within the immune system to mediate cell-cell interactions. The functional forms of CD8 consist of either a heterodimer of two isoforms, CD8alpha and CD8beta, or a homodimer of two CD8alpha molecules. CD8 acts as a coreceptor to facilitate binding between the T-cell Receptor (TCR) and the class I Major Histocompatibility Complex (MHC). Studying CD8 and its importance in isoimmunity can further our understanding of post-transplant recognition. The CD8a (CD8alpha, CD8 alpha) Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. The particles contain a human CD8a (NM_001768.6) driven by an EF1a promoter and a puromycin selection marker.)

-80°C

41115812

Human