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CD8(RIV11), CF405S conjugate, 0.1mg/mL [26628-22-8]

CD8(RIV11), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC040333
Biotium
ApplicationsFlow Cytometry, ImmunoFluorescence
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetCD8A
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Overview

  • Supplier
    Biotium
  • Product Name
    CD8(RIV11), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    RIV11
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID925
  • Target name
    CD8A
  • Target description
    CD8a molecule
  • Target synonyms
    CD8; CD8 antigen, alpha polypeptide (p32); Leu2; Leu2 T-lymphocyte antigen; OKT8 T-cell antigen; p32; T cell co-receptor; T8 T-cell antigen; T-cell antigen Leu2; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP01732
  • Protein Name
    T-cell surface glycoprotein CD8 alpha chain
  • Scientific Description
    Recognizes a protein of 32 kDa, identified as CD8a (also known as CD8 chain, T cell co-receptor, Leu2, and T8). CD8 molecule consists of two chains, termed and chain, which are expressed as a disulphide-linked heterodimer or as an homodimer. CD8 is expressed on T cell subset (cytotoxic/suppressor T cells), thymocytes and NK cells. The majority of CD8 T-cells expresses CD8 as heterodimer. Some subpopulation of CD8 T cells as well as NK cells may express homodimer. CD8 functions as a co-receptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 chain (but not chain). The cytoplasmic domain of CD8 associates with p56lck tyrosine kinase. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203