IHC-P analysis of mouse testis tissue using GTX52005 CDC14A antibody. Antigen retrieval : Boiling in sodium citrate buffer (pH6) for 15min Dilution : 1:400
IHC-P analysis of mouse testis tissue using GTX52005 CDC14A antibody. Antigen retrieval : Boiling in sodium citrate buffer (pH6) for 15min Dilution : 1:400
CDC14A antibody
GTX52005
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCDC14A
Overview
- SupplierGeneTex
- Product NameCDC14A antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:300-1000. IHC-P: 1:50-400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8556
- Target nameCDC14A
- Target descriptioncell division cycle 14A
- Target synonymsDFNB105, DFNB32, DFNB35, cdc14, hCDC14, dual specificity protein phosphatase CDC14A, CDC10 (cell division cycle 10, S. cerevisiae, homolog), CDC14 cell division cycle 14 homolog A
- HostRabbit
- IsotypeIgG
- Protein IDQ9UNH5
- Protein NameDual specificity protein phosphatase CDC14A
- Scientific DescriptionThe protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Imtiaz A, Belyantseva IA, Beirl AJ, et al. CDC14A phosphatase is essential for hearing and male fertility in mouse and human. Hum Mol Genet. 2018,27(5):780-798. doi: 10.1093/hmg/ddx440Read this paper
- Falsetta ML, Foster DC, Woeller CF, et al. Toll-Like Receptor Signaling Contributes to Proinflammatory Mediator Production in Localized Provoked Vulvodynia. J Low Genit Tract Dis. 2018,22(1):52-57. doi: 10.1097/LGT.0000000000000364Read this paper
Datasheet
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