IHC-P analysis of mouse testis tissue using GTX52005 CDC14A antibody. Antigen retrieval : Boiling in sodium citrate buffer (pH6) for 15min Dilution : 1:400
IHC-P analysis of mouse testis tissue using GTX52005 CDC14A antibody. Antigen retrieval : Boiling in sodium citrate buffer (pH6) for 15min Dilution : 1:400
CDC14A antibody
GTX52005
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetCDC14A
Overview
- SupplierGeneTex
- Product NameCDC14A antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:300-1000. IHC-P: 1:50-400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8556
- Target nameCDC14A
- Target descriptioncell division cycle 14A
- Target synonymsCDC10 (cell division cycle 10, S. cerevisiae, homolog); cdc14; CDC14 cell division cycle 14 homolog A; DFNB105; DFNB32; DFNB35; dual specificity protein phosphatase CDC14A; hCDC14
- HostRabbit
- IsotypeIgG
- Protein IDQ9UNH5
- Protein NameDual specificity protein phosphatase CDC14A
- Scientific DescriptionThe protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- CDC14A phosphatase is essential for hearing and male fertility in mouse and human. Imtiaz A et al., 2018 Mar 1, Hum Mol GenetRead more
- Toll-Like Receptor Signaling Contributes to Proinflammatory Mediator Production in Localized Provoked Vulvodynia. Falsetta ML et al., 2018 Jan, J Low Genit Tract DisRead more