
Western blot of human T47D cells showing phospho-specific immunolabeling of the ~34k cdc2 protein phosphorylated at Tyr 15. In lane 2, cells were treated with EGF leading to dephosphorylation of Tyr 15 using CDC2 (phospho Tyr15) antibody (GTX82728).
CDC2 (phospho Tyr15) antibody
GTX82728
Overview
- SupplierGeneTex
- Product NameCDC2 (phospho Tyr15) antibody
- Delivery Days Customer9
- Application Supplier NoteOptimal working dilutions should be determined experimentally by the end user.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID983
- Target nameCDK1
- Target descriptioncyclin dependent kinase 1
- Target synonymsCDC2; CDC28A; cell cycle controller CDC2; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; cell division protein kinase 1; cyclin-dependent kinase 1; p34 protein kinase; P34CDC2
- HostRabbit
- IsotypeIgG
- Protein IDP06493
- Protein NameCyclin-dependent kinase 1
- Scientific DescriptionThe protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
- ReactivityHuman, Xenopus
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203