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CDDO-dhTFEA [1191265-33-4]

Research Use Only
T13604
TargetMol Chemicals
CAS Number1191265-33-4
Product group Chemicals
Estimated Purity98.88%
Molecular Weight574.72
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CDDO-dhTFEA [1191265-33-4]
  • Delivery Days Customer
    4
  • CAS Number
    1191265-33-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    CDDO-dhTFEA
  • Estimated Purity
    98.88%
  • Molecular Formula
    C33H45F3N2O3
  • Molecular Weight
    574.72
  • Scientific Description
    CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-kappaB pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expression of related genes, attenuates NF-kappaB and transforming growth factor-beta pathway activation, and mitigates glomerulosclerosis, interstitial fibrosis, and inflammation in rats with chronic kidney disease (CKD).
  • Shelf life instruction
    3 years
  • SMILES
    [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)[C@]2([H])C(=O)C[C@@]2([H])[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(=C[C@]21C)C#N)C(=O)NCC(F)(F)F
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200