CDH16 Polyclonal Antibody
![Research Use Only](static/images/certificates/ruo.jpg)
RD84776A
ApplicationsImmunoFluorescence, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCDH16
Overview
- SupplierReddot Biotech
- Product NameCDH16 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence, ImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1014
- Target nameCDH16
- Target descriptioncadherin 16
- Target synonymscadherin 16, KSP-cadherin; cadherin-16; kidney-specific cadherin; KSP-cadherin
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203