ProductsBack/Cdh2 antibody

Cdh2 antibody

Name: Cdh2 antibody
SKU: GTX125962_G10
Availability: BackOrder

GTX125962

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityZebra Fish

Targetcdh2

Overview

Supplier
GeneTex
Product Name
Cdh2 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-Wm: 1:50-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.49 mg/ml
Conjugate
Unconjugated
Gene ID30291
Target name
cdh2
Target description
cadherin 2, type 1, N-cadherin (neuronal)
Target synonyms
bib, glo, lyr, ncad, pac, wu:fb47h04, cadherin-2, cadherin 2, neuronal, glass onion, labyrinth, n-cadherin, neural cadherin, parachute
Host
Rabbit
Isotype
IgG
Protein IDQ90275
Protein Name
Cadherin-2
Scientific Description
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. N-cadherin may be involved in neuronal recognition mechanism. Controls neural tube morphogenesis. Required to allow mid- and hindbrain neurons to reach and maintain their appropriate positions within the neural tube by restricting neuronal motility within the embryonic mid- and hindbrain.
Reactivity
Zebra Fish
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Ferre-Fernández JJ, Muheisen S, Thompson S, et al. CRISPR-Cas9-mediated functional dissection of the foxc1 genomic region in zebrafish identifies critical conserved cis-regulatory elements. Hum Genomics. 2022,16(1):49. doi: 10.1186/s40246-022-00423-x
Read this paper
Seese SE, Deml B, Muheisen S, et al. Genetic disruption of zebrafish mab21l1 reveals a conserved role in eye development and affected pathways. Dev Dyn. 2021,250(8):1056-1073. doi: 10.1002/dvdy.312
Read this paper
Brandt ZJ, Echert AE, Bostrom JR, et al. Core Hippo pathway components act as a brake on Yap and Taz in the development and maintenance of the biliary network. Development. 2020,147(12). doi: 10.1242/dev.184242
Read this paper
Warga RM, Kane DA. Probing Cadherin Interactions in Zebrafish with E- and N-Cadherin Missense Mutants. Genetics. 2018,210(4):1391-1409. doi: 10.1534/genetics.118.301692
Read this paper
Hendee KE, Sorokina EA, Muheisen SS, et al. PITX2 deficiency and associated human disease: insights from the zebrafish model. Hum Mol Genet. 2018,27(10):1675-1695. doi: 10.1093/hmg/ddy074
Read this paper