CDK-IN-9
HY-150641
Overview
- SupplierMedChem Express
- Product NameCDK-IN-9 [3031561-92-6]
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC21H24N8S
- Molecular Weight420.53
- Scientific DescriptionCDK-IN-9 (compound 24) is a potent CDK inhibitor, also as a molecular glue inducing an interaction between CDK12 and DDB1, with an IC50 values of 4 nM for CDK2/E. CDK-IN-9 leads to polyubiquitination of cyclin K and its subsequent degradation. CDK-IN-9 induce apoptosis through dephosphorylation of retinoblastoma protein and RNA polymerase II[1].
- SMILESNCCSC1=NC2=C(NN=C2C(NCC3=CC=C(C=C3)N4C=CC=N4)=N1)C5CCC5
- UNSPSC12131703