CDK12-IN-2
M31196
CAS Number2244987-03-7
Product group Chemicals
Molecular Weight532.64
Overview
- SupplierAbMole BioScience
- Product NameCDK12-IN-2
- Delivery Days Customer9
- CAS Number2244987-03-7
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular FormulaC32H32N6O2
- Molecular Weight532.64
- Scientific DescriptionCDK12-IN-2 is a potent, selective and nanomolar CDK12 inhibitor (IC50=52 nM). CDK12-IN-2 is also a strong CDK13 inhibitor due to CDK13 is the closest homologue of CDK12. CDK12-IN-2 inhibits the phosphorylation of Ser2 in the C-terminal domain of RNA polymerase II. CDK12-IN-2 can be used an excellent chemical probe for functional studies of CDK12.
- UNSPSC12352200