CDK12-IN-4 [2651196-69-7]
HY-139327
Overview
- SupplierMedChem Express
- Product NameCDK12-IN-4 [2651196-69-7]
- Delivery Days Customer10
- CAS Number2651196-69-7
- CertificationResearch Use Only
- Molecular FormulaC20H20F2N8O
- Molecular Weight426.42
- Scientific DescriptionCDK12-IN-4, a pyrazolotriazine, is a potent CDK12 inhibitor with an IC50 of 0.641 microM at high ATP (2 mM). CDK12-IN-4 has no effect on CDK2/Cyclin E (IC50>20 microM) and CDK9/Cyclin T1 (IC50>20 microM) at high ATP (2 mM) (WO2021116178A1)[1].
- SMILESFC1=C(F)C2=C(N=C(CNC3=NC(N4CCOCC4)=NC5=C(C6CC6)C=NN35)N2)C=C1
- UNSPSC12131703