![CDK12-IN-4 [2651196-69-7] CDK12-IN-4 [2651196-69-7]](https://www.targetmol.com/group3/M00/02/FF/CgoaEWY7PryECbewAAAAACkwKNQ815.png)
CDK12-IN-4 [2651196-69-7]
T40288
Overview
- SupplierTargetMol Chemicals
- Product NameCDK12-IN-4 [2651196-69-7]
- Delivery Days Customer999
- CAS Number2651196-69-7
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameCDK12-IN-4
- Molecular FormulaC20H20F2N8O
- Molecular Weight426.432
- Scientific DescriptionCDK12-IN-4, a pyrazolotriazine compound, exhibits potent inhibition of CDK12 by achieving an IC50 value of 0.641 microM, utilizing high ATP levels (2 mM). Notably, CDK12-IN-4 does not impact CDK2/Cyclin E (IC50 > 20 microM) or CDK9/Cyclin T1 (IC50 > 20 microM) under the influence of high ATP (2 mM) levels (WO2021116178A1).
- Shelf life instruction3 years
- SMILESFc1ccc2nc(CNc3nc(nc4c(cnn34)C3CC3)N3CCOCC3)[nH]c2c1F
- Storage Instruction-20°C
- UNSPSC51202000