CDK2AP1 antibody

GeneTex

CDK2AP1 antibody

9

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

CDK2AP1

cyclin dependent kinase 2 associated protein 1

CDK2-associated protein 1; cyclin-dependent kinase 2-associated protein 1; deleted in oral cancer 1; Deleted in oral cancer-1; DOC1; doc-1; DORC1; p12DOC-1; putative oral cancer suppressor; ST19

Rabbit

IgG

Cyclin-dependent kinase 2-associated protein 1

The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]

-20°C or -80°C,2°C to 8°C

12352203