CDK4/6-IN-14 [2699091-15-9]

MedChem Express

CDK4/6-IN-14 [2699091-15-9]

10

2699091-15-9

Research Use Only

C24H27ClFN7O

483.97

CDK4/6-IN-14 is a potent and highly selective CDK4 and CDK6 (CDK) inhibitor with IC50s of 10 nM and 16 nM, respectively. CDK4/6-IN-14 exhibits more than 60-fold selectivity over CDKs 1, 2, 7, and 9, and shows high selectivity among other 205 kinases[1].

O=C1N(CC)CCC2=C1C=CC(C3=NC(NC4=NC=C(N5CCNCC5)C=C4)=NC=C3F)=C2.Cl

12131703