Western blot analysis of extracts from rat brain cells, using CDK5R1 antibody.
Western blot analysis of extracts from rat brain cells, using CDK5R1 antibody.
CDK5R1 Antibody
CSB-PA932439
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCDK5R1
Overview
- SupplierCusabio
- Product NameCDK5R1 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8851
- Target nameCDK5R1
- Target descriptioncyclin dependent kinase 5 regulatory subunit 1
- Target synonymsCDK5 activator 1; CDK5P35; CDK5R; cyclin-dependent kinase 5 activator 1; NCK5A; neuronal CDK5 activator; p23; p25; p35; p35nck5a; regulatory partner for CDK5 kinase; tau protein kinase II 23kDa subunit; TPKII regulatory subunit
- HostRabbit
- IsotypeIgG
- Protein IDQ15078
- Protein NameCyclin-dependent kinase 5 activator 1
- Scientific Descriptionp35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at Thr-451 and Thr-461 and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution. Tsai L.-H., Nature 371:419-423(1994). Patrick G.N., Nature 402:615-622(1999). Kesavapany S., J. Neurosci. 24:4421-4431(2004).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203