Bio-Connect

CDK8-IN-6 [2415156-27-1]

HY-147716
MedChem Express
CAS Number2415156-27-1
Product group Chemicals
Molecular Weight413.04
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    CDK8-IN-6 [2415156-27-1]
  • Delivery Days Customer
    10
  • CAS Number
    2415156-27-1
  • Certification
    Research Use Only
  • Molecular Formula
    C26H37ClN2
  • Molecular Weight
    413.04
  • Scientific Description
    CDK8-IN-6 (compound 9) is a potent cyclin-dependent kinase 8 (CDK8) inhibitor with an Kd of 13 nM. CDK8-IN-6 shows cytotoxicity for MOLM-13, OCI-AML3, MV4-11, NRK and H9c2 cells with IC50s of 11.2, 7.5, 8.6, 20.5, 12.5-25 microM, respectively. CDK8-IN-6 has the potential for the research of AML-cancer[1].
  • SMILES
    C[C@@]12C(C3=CC(Cl)=CN=C3)=CC[C@@]1([H])[C@]4([H])CC[C@@]5([H])C[C@H](N(C)C)CC[C@]5(C)[C@@]4([H])CC2
  • UNSPSC
    12131703