CDK8-IN-6 [2415156-27-1]
HY-147716
Overview
- SupplierMedChem Express
- Product NameCDK8-IN-6 [2415156-27-1]
- Delivery Days Customer10
- CAS Number2415156-27-1
- CertificationResearch Use Only
- Molecular FormulaC26H37ClN2
- Molecular Weight413.04
- Scientific DescriptionCDK8-IN-6 (compound 9) is a potent cyclin-dependent kinase 8 (CDK8) inhibitor with an Kd of 13 nM. CDK8-IN-6 shows cytotoxicity for MOLM-13, OCI-AML3, MV4-11, NRK and H9c2 cells with IC50s of 11.2, 7.5, 8.6, 20.5, 12.5-25 microM, respectively. CDK8-IN-6 has the potential for the research of AML-cancer[1].
- SMILESC[C@@]12C(C3=CC(Cl)=CN=C3)=CC[C@@]1([H])[C@]4([H])CC[C@@]5([H])C[C@H](N(C)C)CC[C@]5(C)[C@@]4([H])CC2
- UNSPSC12131703