CDK8-IN-7 [2415156-30-6]
HY-147717
Overview
- SupplierMedChem Express
- Product NameCDK8-IN-7 [2415156-30-6]
- Delivery Days Customer10
- CAS Number2415156-30-6
- CertificationResearch Use Only
- Molecular FormulaC30H40N2
- Molecular Weight428.65
- Scientific DescriptionCDK8-IN-7 (compound 12) is a potent and selective cyclin-dependent kinase 8 (CDK8) inhibitor with an Kd of 3.5 nM. CDK8-IN-7 shows cytotoxicity for MOLM-13, OCI-AML3, MV4-11, NRK and H9c2 cells with IC50s of 5.9, 4.8, 5.4, 16.2, 12.5-25 microM, respectively. CDK8-IN-7 has the potential for the research of AML-cancer[1].
- SMILESC[C@@]12C(C3=CC=CC4=C3C=CN=C4)=CC[C@@]1([H])[C@]5([H])CC[C@@]6([H])C[C@H](N(C)C)CC[C@]6(C)[C@@]5([H])CC2
- UNSPSC12131703