Bio-Connect

CDK8-IN-7 [2415156-30-6]

HY-147717
MedChem Express
CAS Number2415156-30-6
Product group Chemicals
Molecular Weight428.65
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CDK8-IN-7 [2415156-30-6]
  • Delivery Days Customer
    10
  • CAS Number
    2415156-30-6
  • Certification
    Research Use Only
  • Molecular Formula
    C30H40N2
  • Molecular Weight
    428.65
  • Scientific Description
    CDK8-IN-7 (compound 12) is a potent and selective cyclin-dependent kinase 8 (CDK8) inhibitor with an Kd of 3.5 nM. CDK8-IN-7 shows cytotoxicity for MOLM-13, OCI-AML3, MV4-11, NRK and H9c2 cells with IC50s of 5.9, 4.8, 5.4, 16.2, 12.5-25 microM, respectively. CDK8-IN-7 has the potential for the research of AML-cancer[1].
  • SMILES
    C[C@@]12C(C3=CC=CC4=C3C=CN=C4)=CC[C@@]1([H])[C@]5([H])CC[C@@]6([H])C[C@H](N(C)C)CC[C@]6(C)[C@@]5([H])CC2
  • UNSPSC
    12131703