CDK9-IN-19 [2479306-60-8]
HY-150562
CAS Number2479306-60-8
Product group Chemicals
Molecular Weight508.47
Overview
- SupplierMedChem Express
- Product NameCDK9-IN-19 [2479306-60-8]
- Delivery Days Customer10
- CAS Number2479306-60-8
- CertificationResearch Use Only
- Molecular FormulaC26H22F2N4O5
- Molecular Weight508.47
- Scientific DescriptionCDK9-IN-19 is a highly potent and selective CDK9 inhibitor with an IC50 value of 2.0 nM. CDK9-IN-19 has excellent cellular antiproliferative activity, moderate pharmacokinetic property and low hERG inhibition. CDK9-IN-19 significantly induces tumour growth inhibition in an MV4-11 xenograft mice model. CDK9-IN-19 can be used for researching acute myeloid leukaemia (AML)[1].
- SMILESO=C1C(C(C)=O)=C(N2CCOCC2)C3=C(O1)C=C(NC4=NC=C(F)C(C5=CC=C(F)C=C5OC)=N4)C=C3
- UNSPSC12131703