Bio-Connect

CDK/HDAC-IN-2 [2580938-58-3]

HY-146276
MedChem Express
CAS Number2580938-58-3
Product group Chemicals
Molecular Weight523.37
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CDK/HDAC-IN-2 [2580938-58-3]
  • Delivery Days Customer
    10
  • CAS Number
    2580938-58-3
  • Certification
    Research Use Only
  • Molecular Formula
    C25H20Cl2N6O3
  • Molecular Weight
    523.37
  • Scientific Description
    CDK/HDAC-IN-2 is a potent HDAC/CDK dual inhibitor with IC50 of 6.4, 0.25, 45, >1000, 8.63, 0.30, >1000 nM for HDAC1, HDAC2, HDAC3, HDAC6,8, CDK1, CDK2, CDK4,6,7, respectively. CDK/HDAC-IN-2 shows excellent antiproliferative activities. CDK/HDAC-IN-2 induces apoptosis and cell cycle arrest at G2/M phase. CDK/HDAC-IN-2 shows potent antitumor efficacy[1].
  • SMILES
    NC1=CC=CC=C1NC(C2=CC=C(C=C2)CNC(C3=NNC=C3NC(C4=C(C=CC=C4Cl)Cl)=O)=O)=O
  • UNSPSC
    12131703