CDK/HDAC-IN-2 [2580938-58-3]
HY-146276
Overview
- SupplierMedChem Express
- Product NameCDK/HDAC-IN-2 [2580938-58-3]
- Delivery Days Customer10
- CAS Number2580938-58-3
- CertificationResearch Use Only
- Molecular FormulaC25H20Cl2N6O3
- Molecular Weight523.37
- Scientific DescriptionCDK/HDAC-IN-2 is a potent HDAC/CDK dual inhibitor with IC50 of 6.4, 0.25, 45, >1000, 8.63, 0.30, >1000 nM for HDAC1, HDAC2, HDAC3, HDAC6,8, CDK1, CDK2, CDK4,6,7, respectively. CDK/HDAC-IN-2 shows excellent antiproliferative activities. CDK/HDAC-IN-2 induces apoptosis and cell cycle arrest at G2/M phase. CDK/HDAC-IN-2 shows potent antitumor efficacy[1].
- SMILESNC1=CC=CC=C1NC(C2=CC=C(C=C2)CNC(C3=NNC=C3NC(C4=C(C=CC=C4Cl)Cl)=O)=O)=O
- UNSPSC12131703