CDKI-73

AbMole BioScience

CDKI-73

9

1421693-22-2

Chemical

Research Use Only

C15H15FN6O2S2

394.45

Cdki-73 (LS-007) is an orally active and highly effective CDK9 inhibitor with Ki values of 4 nM, 4 nM and 3 nM against CDK9, CDK1 and CDK2, respectively. Cdki-73 down-regulates phosphorylation of RNA polymerase II. Cdki-73 is also an inhibitor of Rab11.

CNC1=NC(=C(S1)C2=C(F)C=NC(=N2)NC3=CC(=CC=C3)[S](N)(=O)=O)C

2-8°C, dry, sealed

12352200