The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA687184(CDKN2AIP Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA687184(CDKN2AIP Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200)
CDKN2AIP Antibody
CSB-PA687184
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetCDKN2AIP
Overview
- SupplierCusabio
- Product NameCDKN2AIP Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID55602
- Target nameCDKN2AIP
- Target descriptionCDKN2A interacting protein
- Target synonymsCARF; CDKN2A-interacting protein; collaborates/cooperates with ARF (alternate reading frame) protein; collaborator of ARF
- HostRabbit
- IsotypeIgG
- Protein IDQ9NXV6
- Protein NameCDKN2A-interacting protein
- Scientific DescriptionCDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame)-dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of p53 function. Expression levels of CDKN2AIP and p53 show an inverse relationship that is caused by a negative-feedback control via a proteasome-mediated degradation pathway. CDKN2AIP is expressed ubiquitously across tissue samples and, along with p14 ARF, is localized to the perinucleolar region within the nucleus.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203
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