CDPPB [781652-57-1]

MedChem Express

CDPPB [781652-57-1]

10

781652-57-1

Research Use Only

99.32

C23H16N4O

364.40

CDPPB is a potent, selective and brain penetrant positive allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGluR5), with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5. CDPPB may provide an approach for development of antipsychotic agents[1].

O=C(NC1=CC(C2=CC=CC=C2)=NN1C3=CC=CC=C3)C4=CC=CC(C#N)=C4

-20°C,2°C to 8°C

12352200