CEA Antibody / Carcinoembryonic Antigen

Biorbyt

CEA Antibody / Carcinoembryonic Antigen

10

Optimal dilution of the Carcinoembryonic Antigen antibody should be determined by the researcher.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Immunohistochemistry (FFPE): 1-2ug/ml IHC-P

Research Use Only

Polyclonal

Unconjugated

CEACAM5

CEA cell adhesion molecule 5

CD66e, CEA, cell adhesion molecule CEACAM5, carcinoembryonic antigen related cell adhesion molecule 5, meconium antigen 100

Rabbit

IgG

Cell adhesion molecule CEACAM5

This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

-20°C

12352203