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Cefotiam hydrochloride [66309-69-1]

Cefotiam hydrochloride [66309-69-1]

T1616
TargetMol Chemicals
CAS Number66309-69-1
Product group Chemicals
Estimated Purity98.74%
Molecular Weight598.6
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Cefotiam hydrochloride [66309-69-1]
  • Delivery Days Customer
    4
  • CAS Number
    66309-69-1
  • Certification
    Research Use Only
  • Chemical Name
    Cefotiam hydrochloride
  • Estimated Purity
    98.74%
  • Molecular Formula
    C18H23N9O4S3.2HCl
  • Molecular Weight
    598.6
  • Scientific Description
    Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.Cl.[H][C@]12SCC(CSc3nnnn3CCN(C)C)=C(N1C(=O)[C@H]2NC(=O)Cc1csc(N)n1)C(O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    51280000

References

  • Larrieu D, Britton S, Demir M, et al. Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science. 2014,344(6183):527-32. doi: 10.1126/science.1252651
    Read this paper