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Celastrol

HY-13067
MedChem Express
CAS Number34157-83-0
Product group Chemicals
Estimated Purity99.90
Molecular Weight450.61
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Celastrol [34157-83-0]
  • Delivery Days Customer
    10
  • CAS Number
    34157-83-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.90
  • Molecular Formula
    C29H38O4
  • Molecular Weight
    450.61
  • Scientific Description
    Celastrol (Tripterine;Tripterin) is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 microM. In addition, Celastrol is also an antibiotic with potent antimicrobial activity against standard and clinical methicillin-resistant Staphylococcus aureus (MRSA) strains, inducing oxidative stress and inhibiting DNA synthesis by binding to P5CDH[1][2][3].
  • SMILES
    OC1=C(C2=CC=C3[C@](C)([C@]4(CC[C@]3(C2=CC1=O)C)C)CC[C@@]5(C)CC[C@@](C(O)=O)(C[C@]54[H])C)C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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